Reaction of anhydro sugars with sodium cobalt tetracarbonyl and carbon monoxide | Zendy

Alex Rosenthal | Zendy; J. N. C. Whyte | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Reaction of anhydro sugars with sodium cobalt tetracarbonyl and carbon monoxide

Author(s) -

Alex Rosenthal,

J. N. C. Whyte

Publication year - 1968

Publication title -

canadian journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.323

H-Index - 68

eISSN - 1480-3291

pISSN - 0008-4042

DOI - 10.1139/v68-364

Subject(s) - chemistry , cobalt , methanol , ether , carbon monoxide , sodium , medicinal chemistry , yield (engineering) , organic chemistry , inorganic chemistry , catalysis , materials science , metallurgy

5,6-Anhydro-1,2-O-isopropylidene-α-D-glucofuranose reacts with sodium cobalt tetracarbonyl and carbon monoxide in methanol to afford methyl 6-deoxy-1,2-O-isopropyhdene-α-D-gluco-heptofuranouronate (3) in 82% yield. Treatment of tri-O-acetyl-1,2-anhydro-D-glucopyranose with sodium cobalt tetracarbonyl in ether gives 3,4,6-tri-O-acetyl-D-glucal. The 2,3-anhydro sugars are resistant to cleavage by cobalt tetracarbonyl anion in ether or in methanol. Sugar acetates are de-O-acetylated by treatment with sodium cobalt tetracarbonyl in ether–methanol.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research