Open AccessSTEROIDS: PART IV. CONDENSATION OF CHOLESTAN-3-ONE AND CHOLESTANE-3,6-DIONE WITH FORMALDEHYDE
Author(s) -
Ted H. Waid,
Alfred Taurinš
Publication year - 1960
Publication title -
canadian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.323
H-Index - 68
eISSN - 1480-3291
pISSN - 0008-4042
DOI - 10.1139/v60-267
Subject(s) - chemistry , paraformaldehyde , formaldehyde , cholestane , methylene , condensation , organic chemistry , methane , amine gas treating , medicinal chemistry , thermodynamics , physics
Cholestan-3-one and cholestane-3,6-dione were allowed to react under the conditions of the Mannich reaction with paraformaldehyde and amine hydrochlorides. The products obtained proved to be methylene-bis-ketones, and were formulated as di(2,2′-3-oxocholestanyl)methane and di(4,4′-3,6-dioxocholestanyl)methane respectively.
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