Open AccessBACTERIOSTATS: III. OXYAMINES AND THEIR DERIVATIVES
Author(s) -
A. F. McKay,
D. L. Garmaise,
G. Y. Paris,
S. Gelblum
Publication year - 1960
Publication title -
canadian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.323
H-Index - 68
eISSN - 1480-3291
pISSN - 0008-4042
DOI - 10.1139/v60-050
Subject(s) - chemistry , phosgene , triethylamine , thiourea , sodium hydroxide , urea , medicinal chemistry , organic chemistry , chloride , hydroxide
A number of benzyloxyamines were prepared for conversion into urea and thiourea derivatives. The benzyloxyamine hydrochlorides on treatment with phosgene gave a mixture of the corresponding benzyl 4-(benzyloxy)-allophanate and benzyloxycarbamyl chloride. Triethylamine converted the benzyloxycarbamyl chlorides into the corresponding 1,3,5-tri-(benzyloxy)-isocyanuric acids. The reactions of the allophanates with amines and sodium hydroxide are described.