Open AccessMicrofluidic encapsulation of SN-38 in block copolymer nanoparticles: effect of hydrophobic block composition on loading and release properties
Author(s) -
D. P. Jensen,
Yimeng Cao,
Changhai Lü,
Jeremy E. Wulff,
Matthew G. Moffitt
Publication year - 2019
Publication title -
canadian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.323
H-Index - 68
eISSN - 1480-3291
pISSN - 0008-4042
DOI - 10.1139/cjc-2018-0371
Subject(s) - copolymer , chemistry , amphiphile , ethylene oxide , polymer , nanoparticle , chemical engineering , polymer chemistry , kinetics , controlled release , organic chemistry , physics , quantum mechanics , engineering
A gas–liquid microfluidic reactor was used to prepare polymer nanoparticles (PNPs) containing the drug 7-ethyl-10-hydroxy camptothecin (SN-38) from a series of poly(methyl caprolactone-co-caprolact...
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