Activator–Inhibitor Control of Tissue Growth
Author(s) -
John A. Adam
Publication year - 1991
Publication title -
siam review
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.683
H-Index - 120
eISSN - 1095-7200
pISSN - 0036-1445
DOI - 10.1137/1033101
Subject(s) - activator (genetics) , simple (philosophy) , computer science , computational biology , calculus (dental) , biology , medicine , biochemistry , epistemology , philosophy , receptor , dentistry
This note develops a simple model for the competition between activator and inhibitor control mechanisms in one-dimensional tissue growth. The pedagogic usefulness of such a model is that it is easily accessible to undergraduate applied mathematicians and is suggestive of behavior known to occur in more realistic biological systems (e.g., some types of cancer). The limitations of the model are obvious and can provide a basis for discussion of the applicability of complementary levels of description in mathematical modeling.
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