A clinical trial of levamisole in primary biliary cirrhosis. | Zendy

S Hishon | Zendy; Garry S. Tobin | Zendy; P.J. Ciclitira | Zendy

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A clinical trial of levamisole in primary biliary cirrhosis.

Author(s) -

S Hishon,

Garry S. Tobin,

P.J. Ciclitira

Publication year - 1982

Publication title -

postgraduate medical journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.568

H-Index - 99

eISSN - 1469-0756

pISSN - 0032-5473

DOI - 10.1136/pgmj.58.685.701

Subject(s) - medicine , primary biliary cirrhosis , levamisole , primary (astronomy) , biliary cirrhosis , cirrhosis , clinical trial , gastroenterology , disease , physics , astronomy , autoimmune disease

A small pilot study of levamisole in primary biliary cirrhosis failed to demonstrate any improvement in liver function and immunological abnormalities even in 'early' cases. This may be due to the fact that the defect in the immune system lies in its afferent arm. At present, levamisole, which is potentially toxic, cannot be recommended in conventional doses for the treatment of this disease.

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