Anti-inflammatory action of diltiazem in patients with unstable angina
Author(s) -
Laxman Dubey,
Hesong Zeng
Publication year - 2006
Publication title -
postgraduate medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.568
H-Index - 99
eISSN - 1469-0756
pISSN - 0032-5473
DOI - 10.1136/pgmj.2006.045302
Subject(s) - diltiazem , medicine , interleukin 10 , unstable angina , gastroenterology , cytokine , stable angina , pharmacotherapy , group b , endocrinology , myocardial infarction , calcium
Plasma concentrations of anti-inflammatory cytokine interleukin 10 (IL10) have been shown to be decreased in patients with unstable angina (UA) suggesting that reduced concentrations of IL10 may favour plaque instability and the development of acute coronary syndromes. Diltiazem has been shown to exert beneficial effects in patients with acute coronary syndrome. However, the potential influence of diltiazem on the anti-inflammatory cytokine IL10 in patients with UA has not been investigated. This study was designed to find out the effects of diltiazem on IL10 in UA patients.
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