Amiodarone toxicity presenting as pulmonary mass and peripheral neuropathy: the continuing diagnostic challenge | Zendy

I Azzam | Zendy; Н. Л. Тов | Zendy; Nizar Elias | Zendy; Jochanan E. Naschitz | Zendy

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Amiodarone toxicity presenting as pulmonary mass and peripheral neuropathy: the continuing diagnostic challenge

Author(s) -

I Azzam,

Н. Л. Тов,

Nizar Elias,

Jochanan E. Naschitz

Publication year - 2006

Publication title -

postgraduate medical journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.568

H-Index - 99

eISSN - 1469-0756

pISSN - 0032-5473

DOI - 10.1136/pgmj.2005.040105

Subject(s) - medicine , amiodarone , pulmonary toxicity , lung , radiology , computed tomography , radiography , computed tomographic , pathology , atrial fibrillation

A 64 year old man receiving long term amiodarone treatment presented with dyspnea, cough, and weight loss. Radiographs and computed tomography showed a lung mass with associated multiple pulmonary nodules. Biopsies of the pulmonary mass showed foamy histiocytes without malignant cells. However, findings on FDG-PET scan were consistent with a malignant tumour. These findings on computed tomography and PET scan and the unusually late resolution of the pulmonary lesions after withdrawal of amiodarone treatment posed a challenging diagnostic problem.

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