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Progressive supranuclear palsy.
Author(s) -
K Tawana,
D B Ramsden
Publication year - 2001
Publication title -
molecular pathology
Language(s) - English
Resource type - Journals
ISSN - 1366-8714
DOI - 10.1136/mp.54.6.427
This review concentrates on the molecular pathology of the protein tau, including its expression in various regions of the brain. The role of post-translational modifications in fibrillogenesis is also discussed, particularly hyperphosphorylation and glycation. However, the initiating event that causes aberrant tau processing remains unclear.

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