[123I]beta-CIT SPECT is a useful method for monitoring dopaminergic degeneration in early stage Parkinson's disease | Zendy

Ania Winogrodzka | Zendy

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[123I]beta-CIT SPECT is a useful method for monitoring dopaminergic degeneration in early stage Parkinson's disease

Author(s) -

Ania Winogrodzka

Publication year - 2003

Publication title -

journal of neurology neurosurgery and psychiatry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.391

H-Index - 206

eISSN - 1468-330X

pISSN - 0022-3050

DOI - 10.1136/jnnp.74.3.294

Subject(s) - putamen , dopaminergic , striatum , spect imaging , caudate nucleus , parkinson's disease , dopamine transporter , nuclear medicine , medicine , beta (programming language) , essential tremor , neuroprotection , dopamine receptor d2 , dopamine , endocrinology , psychology , neuroscience , disease , computer science , programming language

To examine the validity of [(123)I]beta-CIT SPECT for monitoring the progression of dopaminergic degeneration in Parkinson's disease; to investigate the influence of short term treatment with D(2)receptor agonists on striatal [(123)I]beta-CIT binding; and to determine the sample size and frequency of SPECT imaging required to demonstrate a significant effect of a putative neuroprotective agent.

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