Guillain-Barre syndrome following zimeldine treatment.
Author(s) -
Jan Fagius,
P. O. Osterman,
Å Sidén,
B.E. Wiholm
Publication year - 1985
Publication title -
journal of neurology neurosurgery and psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.391
H-Index - 206
eISSN - 1468-330X
pISSN - 0022-3050
DOI - 10.1136/jnnp.48.1.65
Subject(s) - guillain barre syndrome , medicine , incidence (geometry) , complication , drug , pediatrics , psychiatry , surgery , physics , optics
Thirteen cases of the Guillain-Barré syndrome are reviewed, all occurring with a similar relationship to recent commencement of treatment with the antidepressive drug zimeldine. The risk of developing Guillain-Barré syndrome was increased about 25-fold among patients receiving zimeldine, as compared with the natural incidence of the disorder. The cases described provide strong evidence that Guillain-Barré syndrome may occur as a specific, probably immunologically mediated, complication of drug therapy.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom