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Guillain-Barre syndrome following zimeldine treatment.
Author(s) -
Jan Fagius,
P. O. Osterman,
Å Sidén,
B.E. Wiholm
Publication year - 1985
Publication title -
journal of neurology neurosurgery and psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.391
H-Index - 206
eISSN - 1468-330X
pISSN - 0022-3050
DOI - 10.1136/jnnp.48.1.65
Subject(s) - guillain barre syndrome , medicine , incidence (geometry) , complication , drug , pediatrics , psychiatry , surgery , physics , optics
Thirteen cases of the Guillain-Barré syndrome are reviewed, all occurring with a similar relationship to recent commencement of treatment with the antidepressive drug zimeldine. The risk of developing Guillain-Barré syndrome was increased about 25-fold among patients receiving zimeldine, as compared with the natural incidence of the disorder. The cases described provide strong evidence that Guillain-Barré syndrome may occur as a specific, probably immunologically mediated, complication of drug therapy.

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