Beneficial vascular risk profile is associated with amyotrophic lateral sclerosis | Zendy

Nadia A. Sutedja | Zendy; Yvonne T. van der Schouw | Zendy; Kathelijn Fischer | Zendy; Eefje M. Sizoo | Zendy; Mark Huisman | Zendy; Jan H. Veldink | Zendy; Leonard H. van den Berg | Zendy

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Beneficial vascular risk profile is associated with amyotrophic lateral sclerosis

Author(s) -

Nadia A. Sutedja,

Yvonne T. van der Schouw,

Kathelijn Fischer,

Eefje M. Sizoo,

Mark Huisman,

Jan H. Veldink,

Leonard H. van den Berg

Publication year - 2011

Publication title -

journal of neurology neurosurgery and psychiatry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.391

H-Index - 206

eISSN - 1468-330X

pISSN - 0022-3050

DOI - 10.1136/jnnp.2010.236752

Subject(s) - medicine , amyotrophic lateral sclerosis , body mass index , homocysteine , diabetes mellitus , confounding , endocrinology , gastroenterology , population , univariate analysis , high density lipoprotein , cardiology , cholesterol , disease , multivariate analysis , environmental health

Reports of increased amyotrophic lateral sclerosis (ALS) with hyperlipidaemia and elevated plasma homocysteine levels as well as cigarette-smoking and polymorphisms in angiogenic genes suggest a role for altered vascular homeostasis in ALS pathogenesis. The authors assessed the association between vascular risk factors and ALS.

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