Open AccessEffects of deep brain stimulation of dorsal versus ventral subthalamic nucleus regions on gait and balance in Parkinson's disease
Author(s) -
Marie E. McNeely,
Tamara Hershey,
Meghan Campbell,
Samer D. Tabbal,
Morvarid Karimi,
Johanna M Hartlein,
Heather M. Lugar,
Fredy J. Revilla,
Joel S. Perlmutter,
Gammon M. Earhart
Publication year - 2011
Publication title -
journal of neurology, neurosurgery and psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1468-330X
pISSN - 0022-3050
DOI - 10.1136/jnnp.2010.232900
Subject(s) - deep brain stimulation , subthalamic nucleus , gait , balance (ability) , physical medicine and rehabilitation , parkinson's disease , neuroscience , dorsum , psychology , medicine , disease , anatomy
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) improves motor function, including gait and stability, in people with Parkinson's disease (PD) but differences in DBS contact locations within the STN may contribute to variability in the degree of improvement. Based on anatomical connectivity, dorsal STN may be preferentially involved in motor function and ventral STN in cognitive function.