Open AccessSafety and tolerability of adjunctive tolcapone treatment in patients with early Parkinson's disease
Author(s) -
Andrew J. Lees,
Vlad Ratziu,
E. Tolosa,
Wolfgang H. Oertel
Publication year - 2006
Publication title -
journal of neurology neurosurgery and psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.391
H-Index - 206
eISSN - 1468-330X
pISSN - 0022-3050
DOI - 10.1136/jnnp.2006.097154
Subject(s) - tolerability , placebo , discontinuation , medicine , elevated transaminases , adverse effect , gastroenterology , anesthesia , alternative medicine , pathology
The safety and tolerability of adjunctive tolcapone initiated simultaneously with levodopa was evaluated with a focus on increases in liver transaminase and hepatotoxicity.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom