A voxel based morphometry study on mild cognitive impairment | Zendy

Corina Pennanen | Zendy

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A voxel based morphometry study on mild cognitive impairment

Author(s) -

Corina Pennanen

Publication year - 2004

Publication title -

journal of neurology neurosurgery and psychiatry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.391

H-Index - 206

eISSN - 1468-330X

pISSN - 0022-3050

DOI - 10.1136/jnnp.2004.035600

Subject(s) - atrophy , dementia , voxel based morphometry , temporal lobe , magnetic resonance imaging , voxel , psychology , medicine , cognitive impairment , population , parietal lobe , inferior parietal lobule , cognition , neuroscience , pathology , disease , radiology , white matter , epilepsy , environmental health

Mild cognitive impairment (MCI) is the most widely used concept in classifying cognitive impairment in the elderly who do not fulfil the criteria for dementia. MCI is considered to confer an increased risk of progressing to dementia and most often Alzheimer's disease (AD). Various approaches such as imaging of the brain have been applied to predict the conversion of MCI to dementia. A number of volumetric magnetic resonance imaging (MRI) studies have detected atrophy of the medial temporal lobe in subjects with MCI, but for the other cerebral regions the results have been inconsistent.

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