Sequence analysis of polymerase chain reaction amplified t(14;18) chromosomal breakpoints in formalin fixed, paraffin wax embedded follicular lymphoma.
Author(s) -
Matthias Volkenandt,
Olaf Koch,
Renato Fanin,
Debabrata Banerjee,
A Seger,
J L Vogel,
E. Bierhoff,
G. Heidl,
Ludwig Neyses,
Joseph R. Bertino
Publication year - 1992
Publication title -
journal of clinical pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.1
H-Index - 127
eISSN - 1472-4146
pISSN - 0021-9746
DOI - 10.1136/jcp.45.3.210
Subject(s) - polymerase chain reaction , follicular lymphoma , breakpoint , lymphoma , paraffin wax , biology , pathology , microbiology and biotechnology , wax , medicine , genetics , gene , chromosome , biochemistry
To determine whether junctional sequences of rearranged chromosomes can be amplified by use of the polymerase chain reaction (PCR) and whether direct sequence analysis of the PCR products is possible, using DNA from formalin fixed, paraffin wax embedded biopsy specimens.
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