Apoptosis is a major cause of so-called “caseous necrosis” in mycobacterial granulomas in HIV-infected patients
Author(s) -
Aidan Leong,
Pongsak Wannakrairot,
Trishe Leong
Publication year - 2007
Publication title -
journal of clinical pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.1
H-Index - 127
eISSN - 1472-4146
pISSN - 0021-9746
DOI - 10.1136/jcp.2007.050690
Subject(s) - caseous necrosis , apoptosis , necrosis , pathology , biology , macrophage , epithelioid cell , tunel assay , granuloma , giant cell , cd8 , immunology , medicine , biopsy , immune system , immunohistochemistry , in vitro , biochemistry
To demonstrate that so-called "caseous necrosis" is the result of apoptosis and investigate the association of B and T cells, and macrophages with the granulomas and their relationship to some apoptosis-related proteins.
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