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A case is presented in which numerous mitotic figures were found in the liver, pancreas, and adrenal glands of a patient who died in uraemia due to acute tubular necrosis. The possibilities of the failure of excretion of a waste product acting as a stimulus to mitosis, or that a mitotic stimulant is released from the acutely ischaemic kidney, are suggested.

INCREASED MITOTIC ACTIVITY IN THE LIVER AND OTHER ORGANS IN A CASE OF ACUTE RENAL TUBULAR NECROSIS