Topical indomethacin effect on neovascularisation of the cornea and on prostaglandin E2 levels. | Zendy

J Frucht | Zendy; H. Zauberman | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Topical indomethacin effect on neovascularisation of the cornea and on prostaglandin E2 levels.

Author(s) -

J Frucht,

H. Zauberman

Publication year - 1984

Publication title -

british journal of ophthalmology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.016

H-Index - 153

eISSN - 1468-2079

pISSN - 0007-1161

DOI - 10.1136/bjo.68.9.656

Subject(s) - medicine , cornea , prostaglandin e2 , ophthalmology , prostaglandin analogue , optometry , glaucoma

The effect of indomethacin 1% drops against a placebo (NaCl 0.9% solution) was tested in rabbits' corneas injured by a standardized chemical burn. The corneas treated with indomethacin 1% had less neovascularisation and a much smaller increase in the PGE2 levels as compared with the control fellow eyes treated with a placebo. It appears that indomethacin 1% drops have a clear effect on the inflammatory response of the cornea and deserve a clinical trial in selected patients suffering from corneal inflammatory changes.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research