Interlamellar cohesion after corneal crosslinking using riboflavin and ultraviolet A light | Zendy

Gregor Wollensak | Zendy; E. Spörl | Zendy; Cosimo Mazzotta | Zendy; Thomas Kalinski | Zendy; Saadettin Sel | Zendy

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Interlamellar cohesion after corneal crosslinking using riboflavin and ultraviolet A light

Author(s) -

Gregor Wollensak,

E. Spörl,

Cosimo Mazzotta,

Thomas Kalinski,

Saadettin Sel

Publication year - 2011

Publication title -

british journal of ophthalmology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.016

H-Index - 153

eISSN - 1468-2079

pISSN - 0007-1161

DOI - 10.1136/bjo.2010.190843

Subject(s) - keratoconus , microkeratome , ultimate tensile strength , ophthalmology , ultraviolet light , ultraviolet a , medicine , riboflavin , lamellar structure , cornea , materials science , chemistry , composite material , biochemistry , photochemistry , dermatology , keratomileusis

Collagen crosslinking treatment of progressive keratoconus using the photosensitiser riboflavin and ultraviolet A light of 370 nm wavelength has been shown to increase significantly the tensile strength of corneal collagen by about 300%. In keratoconus, interlamellar and interfibrillar slippage have been proposed as pathogenetic mechanisms. Therefore, the aim of this study was to assess the impact of collagen crosslinking on the interlamellar cohesive force.

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