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HLA-DRB1*0102 is associated with TINU syndrome and bilateral, sudden-onset anterior uveitis but not with interstitial nephritis alone
Author(s) -
F. Mackensen,
F. David,
Vedat Schwenger,
Lynnelle K. Smith,
Raja Rajalingam,
Ralph D. Levinson,
C. R. Austin,
Donald C. Houghton,
Tammy M. Martin,
J. T. Rosenbaum
Publication year - 2010
Publication title -
british journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.016
H-Index - 153
eISSN - 1468-2079
pISSN - 0007-1161
DOI - 10.1136/bjo.2010.187955
Subject(s) - medicine , uveitis , cohort , gastroenterology , incidence (geometry) , human leukocyte antigen , immunology , antigen , physics , optics
Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare form of uveitis. Previously, the authors had demonstrated a strong association of human leukocyte antigen (HLA) DRB1*0102 with TINU. Here, the authors performed HLA analysis on subjects with isolated bilateral sudden-onset uveitis (as in the TINU subtype) or with isolated tubulointerstitial nephritis (TIN).

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