Elevated Cerebrospinal Fluid Anti-CD4 Autoantibody Levels in HIV Associate with Neuroinflammation | Zendy

Da Cheng | Zendy; Zhenwu Luo | Zendy; Xiaoyu Fu | Zendy; Sophie Stephenson | Zendy; Clara Di Germanio | Zendy; Philip J. Norris | Zendy; Dietmar Fuchs | Zendy; Lishomwa C. Ndhlovu | Zendy; QuanZhen Li | Zendy; Henrik Zetterberg | Zendy; Magnus Gisslén | Zendy; Richard W. Price | Zendy; Shifang Peng | Zendy; Wei Jiang | Zendy

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Elevated Cerebrospinal Fluid Anti-CD4 Autoantibody Levels in HIV Associate with Neuroinflammation

Author(s) -

Da Cheng,

Zhenwu Luo,

Xiaoyu Fu,

Sophie Stephenson,

Clara Di Germanio,

Philip J. Norris,

Dietmar Fuchs,

Lishomwa C. Ndhlovu,

QuanZhen Li,

Henrik Zetterberg,

Magnus Gisslén,

Richard W. Price,

Shifang Peng,

Wei Jiang

Publication year - 2022

Publication title -

microbiology spectrum

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.502

H-Index - 51

ISSN - 2165-0497

DOI - 10.1128/spectrum.01975-21

Subject(s) - neuroinflammation , immunology , antibody dependent cell mediated cytotoxicity , cerebrospinal fluid , cd8 , medicine , immunoglobulin g , cd14 , immune system , antibody , inflammation , monoclonal antibody

This study reports that an autoantibody presents in the CNS of HIV patients and that its levels in the CSF correlate with some markers of neuroinflammation.

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