Open AccessMultisite Clinical Validation of Isothermal Amplification-Based SARS-CoV-2 Detection Assays Using Different Sampling Strategies
Author(s) -
Kanan Desai,
Karla Alfaro,
Laura Mendoza,
Matthew L. Faron,
Brian Mesich,
Mauricio Maza,
Rhina Domínguez,
Adriana Valenzuela,
Chyntia Díaz Acosta,
M. Martínez,
Juan C. Felix,
Rachel Masch,
Jennifer S. Smith,
Sofia Gabrilovich,
Tracy Wu,
Michael Plump,
Akiva P. Novetsky,
Mark H. Einstein,
Nataki C. Douglas,
Miriam Cremer,
Nicolas Wentzensen
Publication year - 2021
Publication title -
microbiology spectrum
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.502
H-Index - 51
ISSN - 2165-0497
DOI - 10.1128/spectrum.00846-21
Subject(s) - loop mediated isothermal amplification , medicine , sampling (signal processing) , covid-19 , biology , disease , dna , genetics , filter (signal processing) , computer science , infectious disease (medical specialty) , computer vision
Numerous SARS-CoV-2 detection assays have been developed and introduced into the market under emergency use authorizations (EUAs). EUAs are granted primarily based on small studies of analytic sensitivity and specificity with limited clinical validations.