A Multiplex Noninvasive Salivary Antibody Assay for SARS-CoV-2 Infection and Its Application in a Population-Based Survey by Mail | Zendy

Andrey I. Egorov | Zendy; Shan M. Griffin | Zendy; Miyu Fuzawa | Zendy; Jason Kobylanski | Zendy; Rachel D. Grindstaff | Zendy; William T. Padgett | Zendy; Steven O. Simmons | Zendy; Daniel R. Hallinger | Zendy; Jennifer N. Styles | Zendy; Lindsay Wickersham | Zendy; Elizabeth Sams | Zendy; Edward Hudgens | Zendy; Timothy J. Wade | Zendy

Open Access

A Multiplex Noninvasive Salivary Antibody Assay for SARS-CoV-2 Infection and Its Application in a Population-Based Survey by Mail

Author(s) -

Andrey I. Egorov,

Shan M. Griffin,

Miyu Fuzawa,

Jason Kobylanski,

Rachel D. Grindstaff,

William T. Padgett,

Steven O. Simmons,

Daniel R. Hallinger,

Jennifer N. Styles,

Lindsay Wickersham,

Elizabeth Sams,

Edward Hudgens,

Timothy J. Wade

Publication year - 2021

Publication title -

microbiology spectrum

Language(s) - English

Resource type - Journals

ISSN - 2165-0497

DOI - 10.1128/spectrum.00693-21

Subject(s) - saliva , multiplex , antibody , medicine , immunoassay , asymptomatic , immunology , seroprevalence , confidence interval , virology , serology , coronavirus , covid-19 , biology , disease , bioinformatics , infectious disease (medical specialty)

Given the enormous impacts of the COVID-19 pandemic, developing tools for population surveillance of infection is of paramount importance. This article describes the development of a multiplex immunoassay on a Luminex platform to measure salivary immunoglobulin G responses to the spike protein, its two subunits and receptor binding domain, and the nucleocapsid protein of SARS-CoV-2.

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