Identification of Novel Mutations in the N Gene of SARS-CoV-2 That Adversely Affect the Detection of the Virus by Reverse Transcription-Quantitative PCR | Zendy

Rashedul Hasan | Zendy; Mohammad Enayet Hossain | Zendy; Mojnu Miah | Zendy; Md. Mahmudul Hasan | Zendy; Mustafizur Rahman | Zendy; Mohammed Ziaur Rahman | Zendy

Open Access

Identification of Novel Mutations in the N Gene of SARS-CoV-2 That Adversely Affect the Detection of the Virus by Reverse Transcription-Quantitative PCR

Author(s) -

Rashedul Hasan,

Mohammad Enayet Hossain,

Mojnu Miah,

Md. Mahmudul Hasan,

Mustafizur Rahman,

Mohammed Ziaur Rahman

Publication year - 2021

Publication title -

microbiology spectrum

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.502

H-Index - 51

ISSN - 2165-0497

DOI - 10.1128/spectrum.00545-21

Subject(s) - covid-19 , biology , reverse transcriptase , gene , primer (cosmetics) , virus , virology , identification (biology) , genetics , reverse transcription polymerase chain reaction , polymerase chain reaction , computational biology , gene expression , medicine , infectious disease (medical specialty) , chemistry , botany , disease , organic chemistry , pathology , outbreak

Accurate and timely diagnosis of SARS-CoV-2 is a critical step toward controlling the viral spread, since it facilitates the identification and isolation of infected individuals. Mutations in the primer-/probe-binding sites may lead to false-negative results.

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