SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease Outcomes | Zendy

Brenda MartínezGonzález | Zendy; María Eugenia Soria | Zendy; Lucía Vázquez-Sirvent | Zendy; Cristina FerrerOrta | Zendy; Rebeca Lobo-Vega | Zendy; Pablo Mínguez | Zendy; Lorena de la Fuente | Zendy; Carlos Lloréns | Zendy; Beatriz Soriano | Zendy; Ricardo Ramos | Zendy; Marta Cortón | Zendy; Rosario LópezRodríguez | Zendy; Carlos GarcíaCrespo | Zendy; Isabel Gallego | Zendy; Ana Isabel de Ávila | Zendy; Jordi Gómez | Zendy; Luis Enjuanes | Zendy; Llanos SalarVidal | Zendy; Jaime Esteban | Zendy; R. FernándezRoblas | Zendy; Ignacio Gadea | Zendy; Carmen Ayuso | Zendy; Javier RuizHornillos | Zendy; Núria Verdaguer | Zendy; Esteban Domingo | Zendy; Celia Perales | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease Outcomes

Author(s) -

Brenda MartínezGonzález,

María Eugenia Soria,

Lucía Vázquez-Sirvent,

Cristina FerrerOrta,

Rebeca Lobo-Vega,

Pablo Mínguez,

Lorena de la Fuente,

Carlos Lloréns,

Beatriz Soriano,

Ricardo Ramos,

Marta Cortón,

Rosario LópezRodríguez,

Carlos GarcíaCrespo,

Isabel Gallego,

Ana Isabel de Ávila,

Jordi Gómez,

Luis Enjuanes,

Llanos SalarVidal,

Jaime Esteban,

R. FernándezRoblas,

Ignacio Gadea,

Carmen Ayuso,

Javier RuizHornillos,

Núria Verdaguer,

Esteban Domingo,

Celia Perales

Publication year - 2022

Publication title -

microbiology spectrum

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.502

H-Index - 51

ISSN - 2165-0497

DOI - 10.1128/spectrum.00221-22

Subject(s) - biology , point mutation , genetics , mutant , mutation , virology , amplicon , mutation frequency , coding region , polymerase chain reaction , gene

The study shows that mutant spectra of SARS-CoV-2 from diagnostic samples differ in point mutation abundance and complexity and that significantly larger values were observed in virus from patients who developed mild COVID-19 symptoms. Mutant spectrum complexity is not a uniform trait among isolates. The nature and location of low-frequency amino acid substitutions present in mutant spectra anticipate great potential for phenotypic diversification of SARS-CoV-2.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research