Open AccessDissemination Routes of Carbapenem and Pan-Aminoglycoside Resistance Mechanisms in Hospital and Urban Wastewater Canalizations of Ghana
Author(s) -
Jose F Delgado-Blas,
Cecilia Valenzuela Agüi,
Elena Marin Rodriguez,
Carlos Serna,
Natalia Montero,
Courage Kosi Setsoafia Saba,
Bruno GonzálezZorn
Publication year - 2022
Publication title -
msystems
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.931
H-Index - 39
ISSN - 2379-5077
DOI - 10.1128/msystems.01019-21
Subject(s) - resistome , wastewater , biology , plasmid , mobile genetic elements , antibiotic resistance , gene , microbiology and biotechnology , genetics , bacteria , environmental engineering , environmental science
Antimicrobial resistance (AMR) is one the major threats to public health today, especially resistance to last-resort compounds for the treatment of critical infections, such as carbapenems and aminoglycosides. Innumerable works have focused on the clinical ambit of AMR, but studies addressing the impact of wastewater cycles on the emergence and dissemination of resistant bacteria are still limited.