Targeted Conservative Cointegrate Formation Mediated by IS 26 Family Members Requires Sequence Identity at the Reacting End | Zendy

Christopher J. Harmer | Zendy; Ruth M. Hall | Zendy

Open Access

Targeted Conservative Cointegrate Formation Mediated by IS 26 Family Members Requires Sequence Identity at the Reacting End

Author(s) -

Christopher J. Harmer,

Ruth M. Hall

Publication year - 2021

Publication title -

msphere

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.749

H-Index - 39

ISSN - 2379-5042

DOI - 10.1128/msphere.01321-20

Subject(s) - gram , genetics , gene , antibiotic resistance , biology , sequence (biology) , antibiotics , gram negative bacteria , microbiology and biotechnology , bacteria , escherichia coli

The IS 26 family includes the ISs that are commonly found associated with antibiotic resistance genes in multiply resistant Gram-negative and Gram-positive bacteria. IS 26 is most prevalent in Gram-negative species and can generate the clusters of antibiotic resistance genes interspersed with directly oriented IS 26 seen in multiply resistant pathogens.

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