Uncovering the Harms of Treating Clostridioides difficile Colonization | Zendy

Christopher R. Polage | Zendy; Nicholas Turner | Zendy

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Uncovering the Harms of Treating Clostridioides difficile Colonization

Author(s) -

Christopher R. Polage,

Nicholas Turner

Publication year - 2021

Publication title -

msphere

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.749

H-Index - 39

ISSN - 2379-5042

DOI - 10.1128/msphere.01296-20

Subject(s) - clostridioides , colonization , vancomycin , diarrhea , medicine , clostridium difficile toxin a , intensive care medicine , antibiotics , microbiology and biotechnology , biology , clostridium difficile , bacteria , staphylococcus aureus , genetics

Patients with toxin-negative Clostridioides difficile -positive diarrhea are often treated with oral vancomycin with the assumption that treatment is more beneficial than harmful. However, this hypothesis has never been formally tested, and recent studies suggest that most such patients recover quickly without treatment and can be colonized rather than infected.

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