Open AccessStaphylococcal Enterotoxin C Subtypes Are Differentially Associated with Human Infections and Immunobiological Activities
Author(s) -
Olivia N. Chuang-Smith,
Patrick M. Schlievert
Publication year - 2021
Publication title -
msphere
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.749
H-Index - 39
ISSN - 2379-5042
DOI - 10.1128/msphere.01153-20
Subject(s) - enterotoxin , microbiology and biotechnology , immunology , staphylococcus aureus , staphylococcus , biology , medicine , virology , bacteria , escherichia coli , gene , genetics
Staphylococcal enterotoxin C has four subtypes that cause human diseases, designated SEC-1 to -4. This study shows that SEC-2 and SEC-3 are the most toxic subtypes in a rabbit model and are associated with human vaginal infections or colonization in association with another superantigen, toxic shock syndrome toxin 1.
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