NanH Is Produced by Sporulating Cultures of Clostridium perfringens Type F Food Poisoning Strains and Enhances the Cytotoxicity of C. perfringens Enterotoxin | Zendy

Jihong Li | Zendy; Bruce A. McClane | Zendy

Open Access

NanH Is Produced by Sporulating Cultures of Clostridium perfringens Type F Food Poisoning Strains and Enhances the Cytotoxicity of C. perfringens Enterotoxin

Author(s) -

Jihong Li,

Bruce A. McClane

Publication year - 2021

Publication title -

msphere

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.749

H-Index - 39

ISSN - 2379-5042

DOI - 10.1128/msphere.00176-21

Subject(s) - clostridium perfringens , enterotoxin , microbiology and biotechnology , virulence , sialidase , biology , lysis , cytotoxicity , strain (injury) , spore , toxin , in vitro , gene , bacteria , escherichia coli , biochemistry , neuraminidase , enzyme , genetics , anatomy

Clostridium perfringens type F strains cause the second most common bacterial foodborne illness in the United States. C. perfringens enterotoxin (CPE) is responsible for the diarrhea and cramping symptoms of this food poisoning (FP). Previous studies showed that NanI sialidase can enhance CPE activity in vitro .

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