Evidence for multiple major histocompatibility class II X-box binding proteins.
Author(s) -
Antonio Celada,
Richard A. Maki
Publication year - 1989
Publication title -
molecular and cellular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.14
H-Index - 327
eISSN - 1067-8824
pISSN - 0270-7306
DOI - 10.1128/mcb.9.11.5219
Subject(s) - biology , genetics , dna , gene , major histocompatibility complex , dna binding protein , computational biology , sequence (biology) , histocompatibility , promoter , class (philosophy) , microbiology and biotechnology , transcription factor , human leukocyte antigen , gene expression , antigen , artificial intelligence , computer science
The X box is a loosely conserved DNA sequence that is located upstream of all major histocompatibility class II genes and is one of the cis-acting regulatory elements. Despite the similarity between all X-box sequences, each promoter-proximal X box in the mouse appears to bind a separate nuclear factor.
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