Developmental and tissue-specific expression of U4 small nuclear RNA genes. | Zendy

Gina M. Korf | Zendy; Ihab W. Botros | Zendy; William E. Stumph | Zendy

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Developmental and tissue-specific expression of U4 small nuclear RNA genes.

Author(s) -

Gina M. Korf,

Ihab W. Botros,

William E. Stumph

Publication year - 1988

Publication title -

molecular and cellular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.14

H-Index - 327

eISSN - 1067-8824

pISSN - 0270-7306

DOI - 10.1128/mcb.8.12.5566

Subject(s) - biology , rna , small nuclear rna , rna editing , gene , non coding rna , rna splicing , intron , rna induced transcriptional silencing , gene expression , rna silencing , post transcriptional modification , genetics , microbiology and biotechnology , rna interference

U4 RNA is one of several small nuclear RNAs involved in the splicing of mRNA precursors. The domestic chicken has two genes per haploid genome that are capable of encoding U4 RNA. The U4X RNA gene (which encodes a sequence variant of U4 RNA that was unknown prior to the cloning of the gene) and the U4B RNA gene were both expressed in vivo in each of seven adult and three embryonic chicken tissues examined. However, the ratio of U4B RNA to U4X RNA can vary more than sevenfold in both a tissue- and stage-specific manner.

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