Open AccessTumor promoter-inducible genes are differentially expressed in the developing mouse.
Author(s) -
M T Tippetts,
Brian Varnum,
Robert W. Lim,
Harvey R. Herschman
Publication year - 1988
Publication title -
molecular and cellular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.14
H-Index - 327
eISSN - 1067-8824
pISSN - 0270-7306
DOI - 10.1128/mcb.8.10.4570
Subject(s) - biology , gene , genetics , context (archaeology) , gene expression , regulation of gene expression , microbiology and biotechnology , paleontology
TIS genes are rapidly and transiently induced by tetradecanoyl phorbol acetate in 3T3 cells. We analyzed the developmental appearance of a number of the TIS genes to determine whether, in a normal physiological context, these genes have common or distinct mechanisms of regulation. Each TIS gene has a distinct tissue specificity and/or developmental profile.