Subnuclear associations of the v-myb oncogene product and actin are dependent on ionic strength during nuclear isolation. | Zendy

W J Boyle | Zendy; M A Baluda | Zendy

Open Access

Subnuclear associations of the v-myb oncogene product and actin are dependent on ionic strength during nuclear isolation.

Author(s) -

W J Boyle,

M A Baluda

Publication year - 1987

Publication title -

molecular and cellular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.14

H-Index - 327

eISSN - 1067-8824

pISSN - 0270-7306

DOI - 10.1128/mcb.7.9.3345

Subject(s) - biology , myb , nuclear matrix , cell nucleus , actin , nuclear protein , microbiology and biotechnology , biochemistry , nucleus , transcription factor , dna , gene , chromatin

The method used to isolate nuclei has a direct effect on the subnuclear association of the v-myb product, p48v-myb, and nuclear actin. Analysis of nuclei subjected to various isolation procedures showed that disruption of native nuclear structure during hypotonic treatment resulted in dissociation of p48v-myb from the nuclear matrix.

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