Open AccessTranscriptional enhancers in the HLA-DQ subregion.
Author(s) -
K E Sullivan,
B. Matija Peterlin
Publication year - 1987
Publication title -
molecular and cellular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.14
H-Index - 327
eISSN - 1067-8824
pISSN - 0270-7306
DOI - 10.1128/mcb.7.9.3315
Subject(s) - biology , enhancer , hla dq , human leukocyte antigen , gene , beta (programming language) , major histocompatibility complex , genetics , histocompatibility , gene expression , microbiology and biotechnology , allele , antigen , haplotype , computer science , programming language
Using transient expression assays, the HLA-DQ alpha and HLA-DQ beta genes of the human major histocompatibility complex were screened for cis-acting regulatory elements. Two regions in the HLA-DQ alpha gene and one in the HLA-DQ beta gene were identified which fulfilled the criteria for transcriptional enhancers.