Determination of DNA sequence changes induced by ethyl methanesulfonate in human cells, using a shuttle vector system. | Zendy

Jane Lebkowski | Zendy; J H Miller | Zendy; M P Calos | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Determination of DNA sequence changes induced by ethyl methanesulfonate in human cells, using a shuttle vector system.

Author(s) -

Jane Lebkowski,

J H Miller,

M P Calos

Publication year - 1986

Publication title -

molecular and cellular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.14

H-Index - 327

eISSN - 1067-8824

pISSN - 0270-7306

DOI - 10.1128/mcb.6.5.1838

Subject(s) - shuttle vector , ethyl methanesulfonate , biology , methyl methanesulfonate , dna , microbiology and biotechnology , mutation , sequence (biology) , dna repair , gene , vector (molecular biology) , genetics , recombinant dna

The DNA sequence changes for 54 mutations induced in human cells by the alkylating agent ethyl methanesulfonate are reported. The mutations were obtained by using a shuttle vector system with the bacterial lacI gene as the target. Of the 54 mutations obtained, 53 were G:C to A:T transitions.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research