Open AccessRole of nuclear genes in expression of a mitochondrial tRNA gene in Saccharomyces cerevisiae.
Author(s) -
M Wesolowski,
C Palleschi,
L Frontali,
H Fukuhara
Publication year - 1983
Publication title -
molecular and cellular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.14
H-Index - 327
eISSN - 1067-8824
pISSN - 0270-7306
DOI - 10.1128/mcb.3.3.371
Subject(s) - biology , gene , nuclear gene , saccharomyces cerevisiae , genetics , mitochondrial dna , mitochondrion , gene expression , transfer rna , yeast , mutation , pair rule gene , phenotype , saccharomyces , microbiology and biotechnology , regulator gene , rna
In yeast mitochondria, most of the isoaccepting species of tyrosyl tRNA are coded by a mitochondrial gene, tyrA. A particular isoaccepting species is coded by a second mitochondrial gene, tyrB. This gene is not expressed in certain strains of yeast which show no deficient phenotype. Genetic crosses between strains expressing or not expressing the tyrB gene demonstrate that expression is controlled by specific nuclear genes and that a mutation of the tyrA gene can be bypassed when the tyrB gene is operative.