Open AccessFusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation.
Author(s) -
Qiang Lü,
Darin L. Wright,
Mark P. Kamps
Publication year - 1994
Publication title -
molecular and cellular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.14
H-Index - 327
eISSN - 1067-8824
pISSN - 0270-7306
DOI - 10.1128/mcb.14.6.3938
Subject(s) - biology , fusion protein , transactivation , homeobox , fusion gene , microbiology and biotechnology , transcription factor , chromosomal translocation , gene , chimeric gene , transcription (linguistics) , oncogene proteins , dna binding protein , regulation of gene expression , genetics , recombinant dna , gene expression , linguistics , philosophy