Identification of an octamer-binding site in the human kappa light-chain enhancer. | Zendy

Keats Nelms | Zendy; Brian Van Ness | Zendy

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Identification of an octamer-binding site in the human kappa light-chain enhancer.

Author(s) -

Keats Nelms,

Brian Van Ness

Publication year - 1990

Publication title -

molecular and cellular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.14

H-Index - 327

eISSN - 1067-8824

pISSN - 0270-7306

DOI - 10.1128/mcb.10.7.3843

Subject(s) - enhancer , histone octamer , biology , immunoglobulin light chain , enhancer rnas , gene , promoter , binding site , microbiology and biotechnology , immunoglobulin heavy chain , genetics , transcription factor , antibody , gene expression , histone , nucleosome

Octamer motifs contribute to the function and tissue specificity of immunoglobulin heavy- and light-chain gene promoters and the heavy-chain enhancer. A variant octamer-binding site within a conserved region of the human kappa light-chain gene enhancer which contributes to the function of this enhancer has been identified.

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