MUNC, an Enhancer RNA Upstream from the MYOD Gene, Induces a Subgroup of Myogenic Transcripts in trans Independently of MyoD | Zendy

Magdalena A. Cichewicz | Zendy; Manjari Kiran | Zendy; Roza Przanowska | Zendy; Ewelina Sobierajska | Zendy; Yoshiyuki Shibata | Zendy; Anindya Dutta | Zendy

Open Access

MUNC, an Enhancer RNA Upstream from the MYOD Gene, Induces a Subgroup of Myogenic Transcripts in trans Independently of MyoD

Author(s) -

Magdalena A. Cichewicz,

Manjari Kiran,

Roza Przanowska,

Ewelina Sobierajska,

Yoshiyuki Shibata,

Anindya Dutta

Publication year - 2018

Publication title -

molecular and cellular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.14

H-Index - 327

eISSN - 1067-8824

pISSN - 0270-7306

DOI - 10.1128/mcb.00655-17

Subject(s) - myod , biology , enhancer , genetics , myod protein , microbiology and biotechnology , gene , gene expression

MyoD upstream noncoding RNA (MUNC) initiates in the distal regulatory region (DRR) enhancer ofMYOD and is formally classified as an enhancer RNA (DRReRNA ). MUNC is required for optimal myogenic differentiation, induces specific myogenic transcripts intrans (MYOD ,MYOGENIN , andMYH3 ), and has a functional human homolog.

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