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New Player in Endosomal Trafficking: Differential Roles of Smad Anchor for Receptor Activation (SARA) Protein
Author(s) -
Victoria Rozés-Salvador,
Sebastián Omar Siri,
Melina M. Musri,
Cecı́lia Conde
Publication year - 2018
Publication title -
molecular and cellular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.14
H-Index - 327
eISSN - 1067-8824
pISSN - 0270-7306
DOI - 10.1128/mcb.00446-18
Subject(s) - endosome , microbiology and biotechnology , smad , biology , signal transduction , multicellular organism , transport protein , cell signaling , intracellular , receptor , cell , biochemistry
The development and maintenance of multicellular organisms require specialized coordination between external cellular signals and the proteins receiving stimuli and regulating responses. A critical role in the proper functioning of these processes is played by endosomal trafficking, which enables the transport of proteins to targeted sites as well as their return to the plasma membrane through its essential components, the endosomes.

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