A Novel Regulatory Axis, CHD1L-MicroRNA 486-Matrix Metalloproteinase 2, Controls Spermatogonial Stem Cell Properties | Zendy

Shanshan Liu | Zendy; Eithne Margaret Maguire | Zendy; Yinshan Bai | Zendy; Li Huang | Zendy; YuRong Liu | Zendy; Liping Xu | Zendy; Iliana Fauzi | Zendy; Shouquan Zhang | Zendy; Qingzhong Xiao | Zendy; NingFang Ma | Zendy

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A Novel Regulatory Axis, CHD1L-MicroRNA 486-Matrix Metalloproteinase 2, Controls Spermatogonial Stem Cell Properties

Author(s) -

Shanshan Liu,

Eithne Margaret Maguire,

Yinshan Bai,

Li Huang,

YuRong Liu,

Liping Xu,

Iliana Fauzi,

Shouquan Zhang,

Qingzhong Xiao,

NingFang Ma

Publication year - 2018

Publication title -

molecular and cellular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.14

H-Index - 327

eISSN - 1067-8824

pISSN - 0270-7306

DOI - 10.1128/mcb.00357-18

Subject(s) - biology , microrna , microbiology and biotechnology , stem cell , regulation of gene expression , wnt signaling pathway , cell growth , gene expression , cancer research , gene , signal transduction , genetics

Spermatogonial stem cells (SSCs) are unipotent germ cells that are at the foundation of spermatogenesis and male fertility. However, the underlying molecular mechanisms governing SSC stemness and growth properties remain elusive.

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