Decreased c-Myc mRNA Stability via the MicroRNA 141-3p/AUF1 Axis Is Crucial for p63α Inhibition of Cyclin D1 Gene Transcription and Bladder Cancer Cell Tumorigenicity | Zendy

Xin Li | Zendy; Zhongxian Tian | Zendy; Honglei Jin | Zendy; Jiheng Xu | Zendy; Xiaohui Hua | Zendy; Huiying Yan | Zendy; Huating Liufu | Zendy; Jingjing Wang | Zendy; Jingxia Li | Zendy; Junlan Zhu | Zendy; Haishan Huang | Zendy; Chuanshu Huang | Zendy

Open Access

Decreased c-Myc mRNA Stability via the MicroRNA 141-3p/AUF1 Axis Is Crucial for p63α Inhibition of Cyclin D1 Gene Transcription and Bladder Cancer Cell Tumorigenicity

Author(s) -

Xin Li,

Zhongxian Tian,

Honglei Jin,

Jiheng Xu,

Xiaohui Hua,

Huiying Yan,

Huating Liufu,

Jingjing Wang,

Jingxia Li,

Junlan Zhu,

Haishan Huang,

Chuanshu Huang

Publication year - 2018

Publication title -

molecular and cellular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.14

H-Index - 327

eISSN - 1067-8824

pISSN - 0270-7306

DOI - 10.1128/mcb.00273-18

Subject(s) - biology , cyclin d1 , cancer research , untranslated region , transcription factor , cell growth , transcription (linguistics) , cell cycle , microbiology and biotechnology , messenger rna , gene , genetics , linguistics , philosophy

Bladder cancer (BC) ranks as the sixth most common cancer in the United States and is the leading cause of death in patients with urinary malignancies. p63 is a member of the p53 family and is believed to function as a tumor suppressor in human BCs.

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