Knockdown of Long Noncoding RNA H19 Represses the Progress of Pulmonary Fibrosis through the Transforming Growth Factor β/Smad3 Pathway by Regulating MicroRNA 140 | Zendy

Xi Wang | Zendy; Zhe Cheng | Zendy; Lingling Dai | Zendy; Tianci Jiang | Zendy; Liuqun Jia | Zendy; Xiaogang Jing | Zendy; Lin An | Zendy; Huan Wang | Zendy; Meng Liu | Zendy

Open Access

Knockdown of Long Noncoding RNA H19 Represses the Progress of Pulmonary Fibrosis through the Transforming Growth Factor β/Smad3 Pathway by Regulating MicroRNA 140

Author(s) -

Xi Wang,

Zhe Cheng,

Lingling Dai,

Tianci Jiang,

Liuqun Jia,

Xiaogang Jing,

Lin An,

Huan Wang,

Meng Liu

Publication year - 2019

Publication title -

molecular and cellular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.14

H-Index - 327

eISSN - 1067-8824

pISSN - 0270-7306

DOI - 10.1128/mcb.00143-19

Subject(s) - gene knockdown , pulmonary fibrosis , downregulation and upregulation , cancer research , biology , transforming growth factor , microrna , bleomycin , idiopathic pulmonary fibrosis , fibrosis , long non coding rna , lung , pathology , microbiology and biotechnology , medicine , cell culture , gene , genetics , chemotherapy

Long noncoding RNAs (lncRNAs) are involved in various human diseases. Recently, H19 was reported to be upregulated in fibrotic rat lung and play a stimulative role in bleomycin (BLM)-induced pulmonary fibrosis in mice.

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