CCN1–Yes-Associated Protein Feedback Loop Regulates Physiological and Pathological Angiogenesis | Zendy

Sangmi Lee | Zendy; Afruja Ahad | Zendy; Michele Luu | Zendy; Sohyun Moon | Zendy; JoyAnn Caesar | Zendy; Wellington V. Cardoso | Zendy; Maria B. Grant | Zendy; Brahim Chaqour | Zendy

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CCN1–Yes-Associated Protein Feedback Loop Regulates Physiological and Pathological Angiogenesis

Author(s) -

Sangmi Lee,

Afruja Ahad,

Michele Luu,

Sohyun Moon,

JoyAnn Caesar,

Wellington V. Cardoso,

Maria B. Grant,

Brahim Chaqour

Publication year - 2019

Publication title -

molecular and cellular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.14

H-Index - 327

eISSN - 1067-8824

pISSN - 0270-7306

DOI - 10.1128/mcb.00107-19

Subject(s) - matricellular protein , biology , cyr61 , microbiology and biotechnology , angiogenesis , phenotype , growth factor , hippo signaling pathway , signal transduction , cancer research , extracellular matrix , gene , genetics , ctgf , receptor

Cellular communication network factor 1 (CCN1) is a dynamically expressed, matricellular protein required for vascular development and tissue repair. TheCCN1 gene is a presumed target of Yes-associated protein (YAP), a transcriptional coactivator that regulates cell growth and organ size.

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