Open AccessThe CovRS Environmental Sensor Directly Controls the ComRS Signaling System To Orchestrate Competence Bimodality in Salivarius Streptococci
Author(s) -
Adrien Knoops,
Florence Vande Capelle,
Laetitia Fontaine,
Marie Verhaegen,
Johann Mignolet,
Philippe Goffin,
Jacques Mahillon,
Andrea Saß,
Tom Coenye,
Laura Ledesma-García,
Pascal Hols
Publication year - 2022
Publication title -
mbio
Language(s) - English
Resource type - Journals
eISSN - 2161-2129
pISSN - 2150-7511
DOI - 10.1128/mbio.03125-21
Subject(s) - streptococcus salivarius , biology , population , microbiology and biotechnology , phenotype , mutant , genetics , gene , bacteria , streptococcus , demography , sociology
Combining production of antibacterial compounds and uptake of DNA material released by dead cells, competence is one of the most efficient survival strategies in streptococci. Yet, this powerful tactic is energy consuming and reprograms the metabolism to such an extent that cell proliferation is transiently impaired.