Open AccessEvolutionary Sweeps of Subviral Parasites and Their Phage Host Bring Unique Parasite Variants and Disappearance of a Phage CRISPR-Cas System
Author(s) -
Angus Angermeyer,
Stephanie G. Hays,
Maria Nguyen,
Fatema-Tuz Johura,
Marzia Sultana,
Munirul Alam,
Kimberley D. Seed
Publication year - 2022
Publication title -
mbio
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.562
H-Index - 121
eISSN - 2161-2129
pISSN - 2150-7511
DOI - 10.1128/mbio.03088-21
Subject(s) - vibrio cholerae , crispr , biology , cholera , el tor , lineage (genetic) , population , bacteriophage , genome , virology , evolutionary biology , host (biology) , genetics , gene , bacteria , medicine , environmental health , escherichia coli
With 1 to 4 million estimated cases annually, cholera is a disease of serious global concern in regions where access to safe drinking water is limited by inadequate infrastructure, inequity, or natural disaster. The Global Task Force on Cholera Control (GTFCC.org) considers outbreak surveillance to be a primary pillar in the strategy to reduce mortality from cholera worldwide.