Complete Genome Sequence of Klebsiella pneumoniae Phage JD001
Author(s) -
Zelin Cui,
Wenbin Shen,
Zheng Wang,
Haotian Zhang,
Rao Me,
Yanchun Wang,
Lingbin Zeng,
Yongzhang Zhu,
Jinhong Qin,
Ping He,
Xiaokui Guo
Publication year - 2012
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.02435-12
Subject(s) - biology , klebsiella pneumoniae , bacteriophage , genome , microbiology and biotechnology , whole genome sequencing , virology , enterobacteriaceae , genetics , gene , escherichia coli
Klebsiella pneumoniae is a member of the family Enterobacteriaceae, opportunistic pathogens that are among the eight most prevalent infectious agents in hospitals. The emergence of multidrug-resistant strains of K. pneumoniae has became a public health problem globally. To develop an effective antimicrobial agent, we isolated a bacteriophage, named JD001, from seawater and sequenced its genome. Comparative genome analysis of phage JD001 with other K. pneumoniae bacteriophages revealed that phage JD001 has little similarity to previously published K. pneumoniae phages KP15, KP32, KP34, and phiKO2. Here we announce the complete genome sequence of JD001 and report major findings from the genomic analysis.
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