Open AccessN -Glycolylneuraminic Acid Binding of Avian and Equine H7 Influenza A Viruses
Author(s) -
Cindy M. Spruit,
Xueyong Zhu,
Ilhan Tomris,
María Ríos Carrasco,
Alvin X. Han,
Frederik Broszeit,
Roosmarijn van der Woude,
Kim M. Bouwman,
Michel M. T. Luu,
Keita Matsuno,
Yoshihiro Sakoda,
Colin A. Russell,
Ian A. Wilson,
GeertJan Boons,
Robert P. de Vries
Publication year - 2022
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.02120-21
Subject(s) - biology , sialic acid , hemagglutinin (influenza) , n acetylneuraminic acid , influenza a virus subtype h5n1 , virology , equine influenza , glycan , binding site , mutation , influenza a virus , phylogenetic tree , amino acid , mutagenesis , glycoprotein , peptide sequence , genetics , virus , gene
Influenza A viruses cause millions of cases of severe illness and deaths annually. To initiate infection and replicate, the virus first needs to bind to a structure on the cell surface, like a key fitting in a lock.